Democratizing cryoEM: Broadening access to an expanding field

For decades, says Bridget Carragher, cryo-EM was a "niche, hole-in-the-wall" field. But in 2017, cryo-EM passed nuclear magnetic resonance (NMR) spectroscopy for number of annual entries in the Protein Data Bank, the world's sole repository for 3D structural data on proteins, nucleic acids, and large biological molecules. And now it's gaining on the granddaddy of structural methods, X-ray crystallography.