Case Studies

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Learn how cryo-EM advances drug development

Case Studies by NIS Clients

CryoTEM in Preclinical Vaccine Development: Characterizing the lead candidate adjuvant formulation

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Negative Staining Electron Microscopy: Unfolding the structural arrangement of domains in single chain diabody

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A team from Janssen Research used an integrative structural biology approach to study human malic enzyme 3 (ME3), a potential therapeutic target for pancreatic cancer.

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Ring Therapeutics solved the first Anellovirus structure by using cryo-EM.

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Merck Used cryo-EM to Gain Insight Into Mechanism of Action by Imaging Structures of Inhibitory Antibodies Complexed with Arginase 1.

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Determine the Absolute Configuration of a New API Early in Drug Development with MicroED.

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Cryo-EM in Ligand Binding Site Studies: Sugar phosphate activation of the stress sensor eIF2B.

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